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pentobarbital will reduce the extent or effect of bexarotene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Observe Closely (1)pentobarbital will lower the level or effect of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Lack of, or decreased reaction to tofacitinib could hap